| 单词 | Deficiencies,Protein S |
| 释义 | Deficiencies,Protein S《英文msh词典》Deficiencies,Protein S [入口词] Deficiencies,Protein S [主题词] Protein S Deficiency [英文释义] An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity,associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein),and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine,12th ed,p1511; Wintrobe's Clinical Hematology,9th ed,p1523) |
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