| 单词 | Dehydrogenase,Isocitrate |
| 释义 | Dehydrogenase,Isocitrate《英文msh词典》Dehydrogenase,Isocitrate [入口词] Dehydrogenase,Isocitrate [主题词] Isocitrate Dehydrogenase [英文释义] An enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate,carbon dioxide,and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+,Mn2+; it is activated by ADP,citrate,and Ca2+,and inhibited by NADH,NADPH,and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (From Dorland,27th ed) (The NADP+ enzyme is EC 1.1.1.42.) EC 1.1.1.41. |
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