单词 | Dehydrogenase,Methylenetetrahydrofolate |
释义 | Dehydrogenase,Methylenetetrahydrofolate《英文msh词典》Dehydrogenase,Methylenetetrahydrofolate [入口词] Dehydrogenase,Methylenetetrahydrofolate [主题词] Methylenetetrahydrofolate Dehydrogenase (NADP) [英文释义] An NADP-dependent oxidoreductase that catalyses the conversion of 5,10-methyleneterahydrofolate to 5,10-methenyl-tetrahydrofolate. In higher eukaryotes a trifunctional enzyme exists with additional METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE and FORMATE-TETRAHYDROFOLATE LIGASE activity. The enzyme plays an important role in the synthesis of 5-methyltetrahydrofolate,the methyl donor for the VITAMIN B12-dependent remethylation of HOMOCYSTEINE to METHIONINE via METHIONINE SYTHASE. |
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