| 单词 | Dermatopolymyositides |
| 释义 | Dermatopolymyositides《英文msh词典》Dermatopolymyositides [入口词] Dermatopolymyositides [主题词] Dermatomyositis [英文释义] A subacute or chronic inflammatory disease of muscle and skin,marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose,cheeks,forehead,upper trunk,and arms. The disease is associated with a complement mediated intramuscular microangiopathy,leading to loss of capillaries,muscle ischemia,muscle-fiber necrosis,and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al.,Principles of Neurology,6th ed,pp1405-6) |
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