| 单词 | Dihydrofolate Dehydrogenase |
| 释义 | Dihydrofolate Dehydrogenase《英文msh词典》Dihydrofolate Dehydrogenase [同义词] Dihydrofolate Dehydrogenase [主题词] Tetrahydrofolate Dehydrogenase [中文释义] 二氢叶酸脱氢酶 [英文释义] An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+,producing reduced folate for amino acid metabolism,purine ring synthesis,and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland,27th ed) EC 1.5.1.3. |
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