《英文msh词典》Alkaloids,Pyrrolizidine
[入口词] Alkaloids,Pyrrolizidine
[主题词] Pyrrolizidine Alkaloids
[英文释义] A group of ALKALOIDS,characterized by a nitrogen-containing necine,occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.