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单词 Alkylated Estrogenic Steroids
释义

Alkylated Estrogenic Steroids


《英文msh词典》Alkylated Estrogenic Steroids
[入口词] Alkylated Estrogenic Steroids
[主题词] Estrogenic Steroids,Alkylated
[药动学] Estrogens
[英文释义] Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable,resistant to metabolic degradation,and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.
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