《英文msh词典》erbB-2 Receptor Protein-Tyrosine Kinase
[同义词] erbB-2 Receptor Protein-Tyrosine Kinase
[主题词] Receptor,erbB-2
[中文释义] erbB2受体蛋白酪氨酸激酶
[英文释义] A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR,EPIDERMAL GROWTH FACTOR),the erbB-3 receptor (RECEPTOR,ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.