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单词 Estrogen Synthetase
释义

Estrogen Synthetase


《英文msh词典》Estrogen Synthetase
[入口词] Estrogen Synthetase
[主题词] Aromatase
[英文释义] An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process,the 19-methyl is removed. This enzyme is membrane-bound,located in the endoplasmic reticulum of estrogen-producing cells of ovaries,placenta,testes,adipose,and brain tissues. Aromatase is encoded by the CYP19 gene,and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
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