| 单词 | alpha-Conotoxin |
| 释义 | alpha-Conotoxin《英文msh词典》alpha-Conotoxin [入口词] alpha-Conotoxin [主题词] Conotoxins [药动学] Calcium Channel Blockers [英文释义] Peptide neurotoxins from the marine fish-hunting snails of the genus Conus. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins,omega-,alpha-,and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology,3rd ed) |
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