| 单词 | alpha Mannosidase |
| 释义 | alpha Mannosidase《英文msh词典》alpha Mannosidase [入口词] alpha Mannosidase [主题词] alpha-Mannosidase [英文释义] An enzyme that catalyzes the HYDROLYSIS of terminal,non-reducing alpha-D-mannose residues in alpha-D-mannosides. The enzyme plays a role in the processing of newly formed N-glycans and in degradation of mature GLYCOPROTEINS. There are multiple isoforms of alpha-mannosidase,each having its own specific cellular location and pH optimum. Defects in the lysosomal form of the enzyme results in a buildup of mannoside intermediate metabolites and the disease ALPHA-MANNOSIDOSIS. |
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