单词 | Factor Hydrolase,Platelet-Activating |
释义 | Factor Hydrolase,Platelet-Activating《英文msh词典》Factor Hydrolase,Platelet-Activating [入口词] Factor Hydrolase,Platelet-Activating [主题词] 1-Alkyl-2-acetylglycerophosphocholine Esterase [英文释义] A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position,but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA,and HYPERCHOLESTEROLEMIA. |
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