《英文msh词典》Factor VIII,Thrombin-Activated
[同义词] Factor VIII,Thrombin-Activated
[主题词] Factor VIIIa
[中文释义] 因子Ⅷ,凝血酶活化的
[英文释义] Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.