《英文MSH词典》FLT1 RTK
[入口词] FLT1 RTK
[主题词] Vascular Endothelial Growth Factor Receptor-1
[英文释义] A 180-kD VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble,alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.