《英文msh词典》Footprinting,DNA
[入口词] Footprinting,DNA
[主题词] DNA Footprinting
[英文释义] A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al.,Glossary of Genetics: Classical and Molecular,5th ed)