| 单词 | gamma-Thromboglobulin |
| 释义 | gamma-Thromboglobulin《英文msh词典》gamma-Thromboglobulin [入口词] gamma-Thromboglobulin [主题词] Platelet Factor 4 [药动学] Coagulants [英文释义] A high-molecular-weight proteoglycan-platelet factor complex which is released from blood platelets by thrombin. It acts as a mediator in the heparin-neutralizing capacity of the blood and plays a role in platelet aggregation. At high ionic strength (I=0.75),the complex dissociates into the active component (molecular weight 29,000) and the proteoglycan carrier (chondroitin 4-sulfate,molecular weight 350,000). The molecule exists in the form of a dimer consisting of 8 moles of platelet factor 4 and 2 moles of proteoglycan. |
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