《英文msh词典》Gene,BRCA1
[入口词] Gene,BRCA1
[主题词] Genes,BRCA1
[英文释义] A tumor suppressor gene (GENES,SUPPRESSOR,TUMOR) located on human chromosome 17 at locus 17q21. Mutations of this gene are associated with the formation of familial breast and ovarian cancer. It encodes a large,nuclear protein that is a component of DNA repair pathways.