| 单词 | Genes,HER-2 |
| 释义 | Genes,HER-2《英文msh词典》Genes,HER-2 [同义词] Genes,HER-2 [主题词] Genes,erbB-2 [中文释义] 基因,HER-2 [英文释义] The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR,ERBB-2),a protein with structural features simular to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythoblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2. |
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