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单词 Glioma-Derived Vascular Endothelial Cell Growth Factor
释义

Glioma-Derived Vascular Endothelial Cell Growth Factor


《英文msh词典》Glioma-Derived Vascular Endothelial Cell Growth Factor
[入口词] Glioma-Derived Vascular Endothelial Cell Growth Factor
[主题词] Vascular Endothelial Growth Factor A
[英文释义] The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as tumor angiogenesis factor and vascular permeability factor. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
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