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单词 Glycoprotein Ib beta
释义

Glycoprotein Ib beta


《英文msh词典》Glycoprotein Ib beta
[入口词] Glycoprotein Ib beta
[主题词] Platelet Glycoprotein GPIb-IX Complex
[英文释义] Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides,GPIb alpha,GPIb beta,and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
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