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单词 gp120 Envelope Glycoprotein,HIV
释义

gp120 Envelope Glycoprotein,HIV


《英文msh词典》gp120 Envelope Glycoprotein,HIV
[入口词] gp120 Envelope Glycoprotein,HIV
[主题词] HIV Envelope Protein gp120
[英文释义] External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kD and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens,most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.
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