单词 | GPIIb-IIIa Receptors |
释义 | GPIIb-IIIa Receptors《英文msh词典》GPIIb-IIIa Receptors [同义词] GPIIb-IIIa Receptors [主题词] Platelet Glycoprotein GPIIb-IIIa Complex [中文释义] GPⅡb-Ⅲa受体 [英文释义] Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such,it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA. |
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