| 单词 | Hageman Factor Fragments |
| 释义 | Hageman Factor Fragments《英文msh词典》Hageman Factor Fragments [入口词] Hageman Factor Fragments [主题词] Factor XIIa [英文释义] Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation,kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein,plasmin,and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII. |
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