《英文msh词典》HIV-1 Envelope Protein gp120
[同义词] HIV-1 Envelope Protein gp120
[主题词] HIV Envelope Protein gp120
[中文释义] HIV-1包膜蛋白质gp120
[英文释义] External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kD and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens,most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.