单词 | HPRTase |
释义 | HPRTase《英文msh词典》HPRTase [入口词] HPRTase [主题词] Hypoxanthine Phosphoribosyltransferase [英文释义] An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine,guanine,or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the LESCH-NYHAN SYNDROME,while partial deficiency results in overproduction of uric acid. EC 2.4.2.8. |
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