《英文msh词典》IGF-I Receptor
[同义词] IGF-I Receptor
[主题词] Receptor,IGF Type 1
[中文释义] IGF-Ⅰ受体
[英文释义] A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor,it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The beta subunit contains an intrisic tyrosine kinase domain.