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单词 Injury,Myocardial Reperfusion
释义

Injury,Myocardial Reperfusion


《英文msh词典》Injury,Myocardial Reperfusion
[入口词] Injury,Myocardial Reperfusion
[主题词] Myocardial Reperfusion Injury
[英文释义] Functional,metabolic,or structural changes in ischemic heart muscle thought to result from REPERFUSION to the ischemic areas. Changes can be fatal to muscle cells and may include edema with explosive cell swelling and disintegration,sarcolemma disruption,fragmentation of mitochondria,contraction band necrosis,enzyme washout,and calcium overload. Other damage may include hemorrhage and ventricular arrhythmias. One possible mechanism of damage is thought to be oxygen free radicals. Treatment currently includes the introduction of scavengers of oxygen free radicals,and injury is thought to be prevented by warm blood cardioplegic infusion prior to reperfusion.
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