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单词 Antibody Dependent Cell Cytotoxicity
释义

Antibody Dependent Cell Cytotoxicity


《英文msh词典》Antibody Dependent Cell Cytotoxicity
[入口词] Antibody Dependent Cell Cytotoxicity
[主题词] Antibody-Dependent Cell Cytotoxicity
[英文释义] The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies,but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a killer cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers,or a monocyte,macrophage,or polynuclear leukocyte,depending on the identity of the target cell. The reaction is complement-independent.
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