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单词 Insulin-Like-Growth Factor Binding Protein-4 Protease
释义

Insulin-Like-Growth Factor Binding Protein-4 Protease


《英文msh词典》Insulin-Like-Growth Factor Binding Protein-4 Protease
[入口词] Insulin-Like-Growth Factor Binding Protein-4 Protease
[主题词] Pregnancy-Associated Plasma Protein-A
[英文释义] A product of the PLACENTA,and DECIDUA,secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS,ovarian FOLLICULAR FLUID,and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500 kDa.
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