| 单词 | Integrin alpha Subunits |
| 释义 | Integrin alpha Subunits《英文msh词典》Integrin alpha Subunits [入口词] Integrin alpha Subunits [主题词] Integrin alpha Chains [英文释义] The alpha subunits of integrin heterodimers (INTEGRINS),which mediate ligand specificity. There are approximately 18 different alpha chains,exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif,and seven 60-amino acid tandem repeats,the last 4 of which form EF-HAND MOTIFS. The intracellular portion is short (>50 AA) with the exception of INTEGRIN ALPHA4. |
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