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单词 Integrin alpha-v beta-3
释义

Integrin alpha-v beta-3


《英文msh词典》Integrin alpha-v beta-3
[入口词] Integrin alpha-v beta-3
[主题词] Integrin alphaVbeta3
[中文释义] 整合素α-v β-3
[英文释义] An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells,and in some tumor cells,where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS,VITRONECTIN).
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