单词 | Anticoagulant,Lupus |
释义 | Anticoagulant,Lupus《英文msh词典》Anticoagulant,Lupus [入口词] Anticoagulant,Lupus [主题词] Lupus Coagulation Inhibitor [英文释义] An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS,SYSTEMIC),ANTIPHOSPHOLIPID SYNDROME,and in a variety of other diseases as well as in healthy individuals. In vitro,the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo,it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications,including fetal death and spontaneous abortion,as well as a variety of hematologic and neurologic complications. |
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