《英文msh词典》Leukocyte-Adhesion Deficiency Syndromes
[入口词] Leukocyte-Adhesion Deficiency Syndromes
[主题词] Leukocyte-Adhesion Deficiency Syndrome
[英文释义] Rare,autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS,LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions,especially defective tissue emigration of neutrophils,leading to recurrent infection.