| 单词 | lpr Mice,MRL |
| 释义 | lpr Mice,MRL《英文msh词典》lpr Mice,MRL [入口词] lpr Mice,MRL [主题词] Mice,Inbred MRL lpr [英文释义] A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome,which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also,the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents. |
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