| 单词 | Metalloproteinase-2,Tissue Inhibitor-of |
| 释义 | Metalloproteinase-2,Tissue Inhibitor-of《英文msh词典》Metalloproteinase-2,Tissue Inhibitor-of [入口词] Metalloproteinase-2,Tissue Inhibitor-of [主题词] Tissue Inhibitor-of Metalloproteinase-2 [药动学] Protease Inhibitors [英文释义] A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21 kD nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo. |
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