单词 | Mineralocorticoid Excess Syndrome,Apparent |
释义 | Mineralocorticoid Excess Syndrome,Apparent《英文msh词典》Mineralocorticoid Excess Syndrome,Apparent [主题词] Mineralocorticoid Excess Syndrome,Apparent [同义词] Apparent Mineralocorticoid Excess Syndrome [英文释义] A hereditary disease characterized by childhood onset HYPERTENSION,hypokalemic alkalosis,and low RENIN and ALDOSTERONE secretion. It results from a defect in the activity of the 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 enzyme which results in inadequate conversion of CORTISOL to CORTISONE. The build up of unprocessed cortisol to levels that stimulate MINERALOCORTICOID RECEPTORS creates the appearance of having excessive MINERALOCORTICOIDS. |
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