| 单词 | MK 0791 |
| 释义 | MK 0791《英文MSH词典》MK 0791 [入口词] MK 0791 [主题词] Cilastatin [药动学] Protease Inhibitors [英文释义] A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic,IMIPENEM,is hydrolyzed by dehydropeptidase-I,which resides in the brush border of the renal tubule,cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukeotriene E4. |
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