| 单词 | MK231 |
| 释义 | MK231《英文MSH词典》MK231 [入口词] MK231 [主题词] Sulindac [药动学] Cyclooxygenase Inhibitors [英文释义] A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically,the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. |
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