《英文MSH词典》MK 803
[入口词] MK 803
[主题词] Lovastatin
[药动学] Hydroxymethylglutaryl-CoA Reductase Inhibitors
[英文释义] A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES),which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.