单词 | MK-803 |
释义 | MK-803《英文MSH词典》MK-803 [入口词] MK-803 [主题词] Lovastatin [药动学] Hydroxymethylglutaryl-CoA Reductase Inhibitors [英文释义] A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES),which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. |
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