| 单词 | mu-Chain Diseases |
| 释义 | mu-Chain Diseases《英文msh词典》mu-Chain Diseases [入口词] mu-Chain Diseases [主题词] Heavy Chain Disease [英文释义] A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal,but they have a deletion extending from part of the variable domain through the first domain of the constant region,so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes. |
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