《英文msh词典》Mutagenesis,Cassette
[同义词] Mutagenesis,Cassette
[主题词] Mutagenesis,Insertional
[中文释义] 诱变,盒式
[英文释义] Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA can be inserted into or adjacent to a cellular proto-oncogene. Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements,or cause unregulated expression of the proto-oncogene resulting in tumor formation.