单词 | Neurotoxicity Syndrome,MPTP |
释义 | Neurotoxicity Syndrome,MPTP《英文msh词典》Neurotoxicity Syndrome,MPTP [入口词] Neurotoxicity Syndrome,MPTP [主题词] MPTP Poisoning [英文释义] A condition caused by the neurotoxin 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. MPTP causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE,SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al.,Principles of Neurology,6th ed,p1072; Neurology 1986 Feb;36(2):250-8) |
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