| 单词 | New Variant Creutzfeldt Jakob Disease |
| 释义 | New Variant Creutzfeldt Jakob Disease《英文msh词典》New Variant Creutzfeldt Jakob Disease [入口词] New Variant Creutzfeldt Jakob Disease [主题词] Creutzfeldt-Jakob Syndrome [英文释义] A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances,personality changes,ATAXIA; APHASIA,visual loss,weakness,muscle atrophy,MYOCLONUS,progressive dementia,and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY,BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med,1998 Dec 31;339(27)) |
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