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单词 NMDA Receptor Ionophore Complex
释义

NMDA Receptor Ionophore Complex


《英文msh词典》NMDA Receptor Ionophore Complex
[入口词] NMDA Receptor Ionophore Complex
[主题词] Receptors,N-Methyl-D-Aspartate
[英文释义] A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
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