英语词汇“NSC612049”的意思、用法、释义、翻译、读音、例句、短语、词组-英汉翻译词典

《英文MSH词典》NSC612049

[入口词] NSC612049

[主题词] Didanosine

[药动学] Reverse Transcriptase Inhibitors

[英文释义] A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication,acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate,its putative active metabolite.

单词	NSC612049
释义	NSC612049 《英文MSH词典》NSC612049 [入口词] NSC612049 [主题词] Didanosine [药动学] Reverse Transcriptase Inhibitors [英文释义] A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication,acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate,its putative active metabolite.
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