单词 | ATP-Binding Cassette,Sub-Family B,Member 1 |
释义 | ATP-Binding Cassette,Sub-Family B,Member 1《英文msh词典》ATP-Binding Cassette,Sub-Family B,Member 1 [入口词] ATP-Binding Cassette,Sub-Family B,Member 1 [主题词] P-Glycoprotein [英文释义] A 170 kD transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals,including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE,MULTIPLE). |
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