《英文msh词典》Oxidase,NADPH
[入口词] Oxidase,NADPH
[主题词] NADPH Oxidase
[英文释义] A plasma membrane-associated enzyme complex that catalyzes the univalent reduction of oxygen using NADPH as an electron donor. The superoxide anion formed acts as an oxidant in the phagocyte microbicidal system,proceeding through a series of electron transfer reactions that form the respiratory burst. Various genetic defects in the system result in chronic granulomatous disease (GRANULOMATOUS DISEASE,CHRONIC). (Dorland,28th ed) EC 1.6.-.