单词 | p185(c-neu) |
释义 | p185(c-neu)《英文msh词典》p185(c-neu) [入口词] p185(c-neu) [主题词] Receptor,erbB-2 [英文释义] A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR,EPIDERMAL GROWTH FACTOR),the erbB-3 receptor (RECEPTOR,ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. |
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