单词 | p190 (MET) |
释义 | p190 (MET)《英文msh词典》p190 (MET) [入口词] p190 (MET) [主题词] Proto-Oncogene Protein c-met [英文释义] A cell surface protein-tyrosine kinase receptor for HEPATOCYTE GROWTH FACTOR. It consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEIN C-MET are associated with papillary renal carcinoma and other neoplasia. |
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